Diode array NIR analyser
SentroPAT DA
The SentroPAT DA is a dedicated NIR analyser designed for non-invasive online monitoring of pharmaceutical powder blending. It utilises diode array technology and provides valuable process insight from product development to operations.
Last updated: June 29, 2024
SentroPAT DA
Diode-array-based NIR analyser
At the core of the SentroPAT DA is a reliable and durable InGaAs diode array spectrometer. Its high spectral resolution and wavelength accuracy, coupled with low noise, make it suitable for use in demanding applications. Its superior system-to-system comparability streamlines method transfer between different instruments. Additionally, its long-term and temperature stability are of the highest quality, supported by internal intensity and wavelength references.
It offers several key benefits, including quantitative analysis of blend constituents using chemometric models, process knowledge for blend time optimisation, elimination of conventional sampling and laboratory analysis, real-time monitoring of blend uniformity, ease-of-use and minimum maintenance, reliable measurement synchronisation to the blender rotation, easy-to-clean surfaces for use in GMP production facilities, and data integrity through embedded buffering and WiFi transmission. The system is also compatible with plant-level IT and controls via OPC-server or interfaces to SIPAT or SynTQ.
Your benefits
- Compatibility with laboratory blenders of various sizes, including small-scale ones
- High analytical quality due to its high spectral resolution and low noise
- Stability and ease of use, thanks to its internal intensity and wavelength references
- Cost-effective solution for pharmaceutical powder blending
- Process interface is compatible with SentroPAT BU II when used with the 4" flange.
- The unit's smooth surfaces are easy to clean, meeting requirements for GMP production facilities.
- Data integrity is supported by the embedded system, with all generated data buffered locally before transmission through WiFi connection.
| Technical Specifications* | *Subject to change without notice | |
|---|---|---|
| Detector | 512 pixel linear InGaAs array | |
| Wavelength range | 1100 - 1900nm | |
| Spectral resolution (FWHM) | Approximately 10nm | |
| Wavelength accuracy | < 1nm | |
| Wavelength reproducibility | < 0.2nm | |
| Photometric linearity | Fulfilling USP <1856> and EP 2.2.40 requirements | |
| Noise - High flux | According to USP<1856> and E.P. 2.2.40 | |
| Noise - Low flux | According to USP<1856> and E.P. 2.2.40 | |
| Light source | 2 x 5W used redundantly for maintenance free operation for > 10 years | |
| Data acquisition time | < 1s (configurable, typically 0.5s) | |
| Sampling interface | Non contact, through sapphire window | |
| Measurement spot size | Approximately 10mm diameter | |
| Measurement trigger | Software controlled by 3 axis accelerometer, synchronised to blender rotation | |
| Power supply | Replaceable Li-Ion battery, > 6 hours operation
External power supply for lab operation and recharging | |
| Enclosure | IP65 / NEMA4, cGMP conform, Aluminum anodised | |
| Dimensions | 170 x 105 x 60mm (W x D x H)
Height: add 36mm for flange | |
| Weight | 2.2Kg | |
| Communications | WiFi (802.11 a/g/n) | |
| Software | SentroSuite GmP, optional interfaces to SiPAT and SynTQ | |
| Validation | Software integrated validation routines according USP<1856>, EP2.2.40 | |
| Service port | Service Connections for HDMI monitor and USB for computer peripherals | |
| Mounting | 4" or 2" sanitary flange | |
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